The importance of gut microbiota
There are about 100 trillion microbes in human gut, and there are about 500-1000 of different species. The number of these microorganisms is 10 times more than human cells, and the total mass is up to two kilograms.
Recent studies showed that intestinal microbes will affect human health and could be regarded as the second genome of humans. Moreover, literatures showed that the imbalance of intestinal microbiota are associated with many diseases, as shown in the following figure:
It takes 6 weeks from sample collection to the issuing of reports.
The principle of 16s rRNA gut microbiome test is based on detecting the sequences of the highly variable region of the 16S rRNA gene in order to identify the microbial flora composition and richness in our gut microbiota. Next Generation Sequencing (NGS) is a non-cultivation method that generating data on the entire microbial population in our samples. These data would undergo a comprehensive analysis to determine the relationship between the gut microbes and risk of a specific disease.
Contents of the report
The main advantage of the 16S rRNA test is the simultaneous detection of the relative abundance of more than 160 different bacterial genera in a single run. These data can provide a relatively complete map of our gut and the following analysis would be included in the report:
Richness and diversity:
In this test, the richness and uniformity of intestinal microflora would be analyzed as the intestinal balance is very important for maintaining our health. Recently studies showed that dysbiosis is associated with many chronic diseases.
Ten core genus of gut microbiota in Chinese population
We will detect ten core genus of gut microbiota which are universal in Chinese population. In 2019, the international academic journal published a paper on the distribution of intestinal microflora of more than one hundred healthy individuals from different provinces in China. The result showed that these ten core genus could be detected in every participants in this project. Therefore, the lack of these genus will reduce the diversity of the intestinal microflora and may lead to different diseases.
Relationship between five major symptoms and microbial flora
We will analyze your microbial flora and the following symptoms in details:
- Obesity and metabolic syndrome
These five different symptoms are affected by the microbial flora of different phylum and genus. For example, Clostridium is a genera that causes diarrhea and Staphylococcus causes allergies and eczema. After analyzing the relative abundance of various microbial phylum and genus in your gut, we can evaluate the risk that your gut flora will cause you to develop a particular symptom. These risk indicators will be combined with your questionnaires to provide a more accurate assessment of your current gut health.
Summary and dietary habits recommendations
In the final part of the report, we will first summarize your intestinal balance results and the relationship between gut flora and the risk assessment of five different disease including metabolic syndrome/obesity, diarrhea, constipation, allergy, eczema. Then, we will provide a series of tailor-made diets and recommendations based on your gut microbiota. These recommendations include getting rid of bad eating habits and changing the proportion of your intake of different nutrients. Finally, we will suggest how to improve your intestinal health.
Testing Price: HK$2800 (including interpretation by professionals)